After the release of Jython 2.2 in August 2007, the focus of the next version of Jython has turned to catching up – pushing out a hopefully CPython 2.5 compatible Jython (that requires Java 1.5).
With just CPython 2.3 compatibility, Jython in theory should be able to run Pylons. A few developers are currently working on getting Pylons and Django running on Jython. Jython wiki pages of interest for Pylons are:
PylonsOnJython
SetuptoolsOnJython
Latest Jython commits: